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Maximize the utility of
imaging biomarkers
to the benefit of
patients with arthritis.
Learn more about the project  

AutoPiX is a major international project focused on improving healthcare for people with rheumatic and musculoskeletal diseases (RMDs).

The AutoPiX project brings together pharmaceutical and medical technology partners with leading academic institutions to enhance the use of imaging biomarkers for patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA), collectively known as systemic arthritides.

It aims to develop advanced imaging tools and artificial intelligence (AI) models to better diagnose, monitor, and treat these conditions. These tools will make use of imaging biomarkers—like X-rays, ultrasounds, and MRIs—to provide more precise and personalised care.

AutoPiX is a major international project focused on improving healthcare for people with rheumatic and musculoskeletal diseases (RMDs).

The AutoPiX project brings together pharmaceutical and medical technology partners with leading academic institutions to enhance the use of imaging biomarkers for patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA), collectively known as systemic arthritides.

It aims to develop advanced imaging tools and artificial intelligence (AI) models to better diagnose, monitor, and treat these conditions. These tools will make use of imaging biomarkers—like X-rays, ultrasounds, and MRIs—to provide more precise and personalised care.

Learn more about the project  
Partners / MoonLake Immunotherapeutics

MoonLake Immunotherapeutics

MoonLake Immunotherapeutics is a clinical-stage biopharmaceutical company unlocking the potential of sonelokimab, a novel investigational Nanobody® for the treatment of inflammatory disease, to revolutionize outcomes for patients. Sonelokimab inhibits IL-17A and IL-17F by inhibiting the IL-17A/A, IL-17A/F, and IL-17F/F dimers that drive inflammation. The company’s focus is on inflammatory diseases with a major unmet need, including hidradenitis suppurativa and psoriatic arthritis – conditions affecting millions of people worldwide with a large need for improved treatment options. MoonLake was founded in 2021 and is headquartered in Zug, Switzerland

What is the role of MoonLake Immunotherapeutics in Autopix

MoonLake Immunotherapeutics conducts a clinical trial (S-OLARIS) together with Prof. Xenofon Baraliakos as the principal investigator. S-OLARIS is an open-label Phase 2 proof-of-concept trial aiming to investigate sonelokimab 60mg administered subcutaneously in approximately 25 patients with active axial spondylarthritis (axSpA). The primary endpoint is the change from baseline (CfB) at week 12 in the uptake of 18F-NaF in the sacroiliac joints and spine using PET in combination with MRI imaging. The study will provide novel insights into the correlation between innovative imaging techniques and established disease pathways in axSpA

Contact

Prof. Dr. med. Kristian Reich
Founder & Chief Scientific Officer
Dr. med. Roman Akbar-Haase
Chief of Staff to the Executive Board